Research archives

COVID-19

• Hopkins C, Alanin M, Philpott C, Harries P, Whitcroft K, Qureishi A, Anari S, Ramakrishnan Y, Sama A, Davies E, Stew B, Gane S, Carrie S, Hathorn I, Bhalla R, Kelly C, Hill N, Boak D, Kumar B N, Management of new onset loss of sense of smell during the COVID‐19 pandemic ‐ BRS Consensus Guidelines, Clinical Otaolaryngology, August 27, 2020

• Galougahi M K, MD, Ghorbani J, MD, Bakhshayeshkaram M, MD, Naeini A S, MD, Haseli, S, Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report, Journal of Academic Radiology, April 13, 2020​​​​​​

• Yan C, MD,  Faraji F, MD PhD, Prajapati D, BS, DeConde A, MD, Boone C, MD PhD, Association of chemosensory dysfunction and Covid‐19 in patients presenting with influenza‐like symptoms, Allergy and Rhinology, April 12, 2020
• Mao L , Jin H, Wang M, Hu Y, Chen S, He Q, Chang J, Hong C, Zhou Y, Wang D, Miao X, Li Y, MD PhD,  Hu B, MD PhD, Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China, JAMA Neurology, April 10, 2020
• Eliezer M MD; Hautefort C MD; Hamel A MD; Verillaud B MD; Herman P MD, PhD; Houdart E MD, PhD; Eloit C MD Sudden and Complete Olfactory Loss Function as a Possible Symptom of COVID-19, JAMA Otolaryngol Head Neck Surg. Published online April 8, 2020. doi:10.1001/jamaoto.2020.0832
• Lechien J, Chiesa-Estomba C, Saussez S, Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study, Rhinology, April 6, 2020
• Gane S, Kelly C, Hopkins C Isolated sudden onset anosmia in COVID-19 infection. A novel syndrome? Rhinology, March 29, 2020
• Bagheri S, Asghari A,  Farhadi M, Shamshiri A, Kabir A, Kamrava S, Jalessi M, Mohebbi A, Alizadeh R, Honarmand A, Ghalehbaghi B, Salimi A, Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak, MedRxiv Preprint March 23, 2020
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Smell Training

• Al Aïn S, Poupon D, Hétu S, Mercier N, Steffener J, Frasnelli J Smell training improves olfactory function and alters brain structure. Neuroimage. April 2019 ;189:45-54.doi: 10.1016
• Pellegrino R, Han P, Reither N, Hummel T Effectiveness of olfactory training on different severities of posttraumatic loss of smell. Laryngoscope. 2019 Mar 8. Aug;129(8):1737-1743. doi: 10.1002/lary.27832. Epub 2019 Mar 8.
• Langdon C, Lehrer E, Berenguer J, Laxe S, Alobid I, Quintó L, Mariño-Sánchez F, Bernabeu M, Marin C, Mullol J Olfactory Training in Post-Traumatic Smell Impairment: Mild Improvement in Threshold Performances: Results from a Randomized Controlled Trial J Neurotrauma. 2018 Nov 15;35(22):2641-2652. doi: 10.1089/neu.2017.5230. Epub 2018 Jul 23
• Wegener B, Croy I, Hahner A, Hummel T Olfactory training with older people. International Journal of Psychiatry 2018 Jan; 212-220
• Oleszkiewicz A, Hanf S, Whitcroft KL, Haehner A, Hummel T Examination of olfactory training effectiveness in relation to its complexity and the cause of olfactory loss Laryngoscope. 2018 Jul;128(7):1518-1522. doi: 10.1002/lary.26985. Epub 2017 Nov 8
• Negoias S, Pietsch K, Hummel T Changes in olfactory bulb volume following lateralized olfactory training Brain Imaging Behav. 2017 Aug;11(4):998-1005. doi: 10.1007/s11682-016-9567-9
• Poletti SC, Michel E, Hummel T Olfactory Training Using Heavy and Light Weight Molecule Odors Perception. 2017 Mar-Apr;46(3-4):343-351. doi: 10.1177/0301006616672881. Epub 2016 Oct 5
• Jiang RS, Twu CW, Liang KL The effect of olfactory training on the odor threshold in patients with traumatic anosmia. Am J Rhinol Allergy. September 2017 ;31(5):317-322.
• Sorokowska A, Drechsler E, Karwowski M, Hummel T Effects of olfactory training: a meta-analysis. Rhinology, 55, March 2017 17-26. doi: 10.4193/Rhin16.195. 
• Patel ZM The evidence for olfactory training in treating patients with olfactory loss. Otolaryngology & Head and Neck Surgery: February 2017 - Volume 25 - Issue 1 - p 43–46
• Konstantinidis I, Tsakiropoulou E, Constantinidis J Long term effects of olfactory training in patients with post-infectious olfactory loss Rhinology. 2016 Jun;54(2):170-5. doi: 10.4193/Rhin15.264

• Mori E, Merkonidis C, Cuevas M, Gudziol V, Matsuwaki Y, Hummel T.​​​​​ The administration of nasal drops in the "Kaiteki" position allows for delivery of the drug to the olfactory cleft: a pilot study in healthy subjects. Eur Arch Otorhinolaryngol. 2016 Apr;273(4):939-43. doi: 10.1007/s00405-015-3701-y. Epub 2015 Jul 4.

• Konstantinidis I, Tsakiropoulou E, Constantinidis J Long term effects of olfactory training in patients with post-infectious olfactory loss; Rhinology 54 - 2 2016; Article 4412.
• Kollndorfer K, Fischmeister FP, Kowalczyk K, Hoche E, Mueller CA, Trattnig S, Schöpf V Olfactory training induces changes in regional functional connectivity in patients with long-term smell loss Neuroimage Clin. 2015 Sep 15;9:401-10. doi: 10.1016/j.nicl.2015.09.004. eCollection 2015
• Mori E, Petters W, Schriever VA, Valder C, Hummel T. Exposure to odours improves olfactory function in healthy children Rhinology. 2015 Sep;53(3):221-6. doi: 10.4193/Rhin14.192.
• Pekala K, Chandra RK, Turner JH. Efficacy of olfactory training in patients with olfactory loss: a systematic review and meta-analysis. Int Forum Allergy Rhinol. 2015; 00:1–7.
• Altundag A, Cayonu M, Kayabasoglu G, Salihoglu M, Tekeli H, Saglam O, Hummel T. Modified olfactory training in patients with post-infectious olfactory loss  Laryngoscope. 2015 Aug;125(8):1763-6. doi: 10.1002/lary.25245. Epub 2015 Jun 2. 
• Geißler K1, Reimann H, Gudziol H, Bitter T, Guntinas-Lichius O. Olfactory training for patients with olfactory loss after upper respiratory tract infections. Eur. Arch Otorhinolaryngol. 2014 Jun; (6):1557-62
• Damm M, Pikart LK, Reimann H, Burkert S, Göktas Ö, Haxel B, Frey S, Charalampakis I, Beule A, Renner B, Hummel T, Hüttenbrink KB. - Olfactory training is helpful in postinfectious olfactory loss: a randomized, controlled, multicenter study. Laryngoscope. 2013 Dec;123(12):E85-90. doi: 10.1002/lary.24390. Epub 2013 Oct 4. PMID: 24114690
• Hummel T, Rissom K, Reden J, Hähner A, Weidenbecher M, Hüttenbrink KB. - Effects of olfactory training in patients with olfactory loss. Int J Otolaryngol. 2012;2012:327206. doi: 10.1155/2012/327206. Epub 2012 May 20. PMID: 22685462

Olfactory Function and Well-being

• Hummel T, Stupka G, Haehner A, Poletti SC Olfactory training changes electrophysiological responses at the level of the olfactory epithelium Rhinology. 2018 Dec 1;56(4):330-335. doi: 10.4193/Rhin17.163
• Boesveldt, S. Yee, J. McClintock,M, Lundström,J Olfactory function and the social lives of older adults: a matter of sex Scientific Reports, volume 7, Article number: 45118 (2017)
• Chung JH, Lee YJ, Kang TW, Kim KR, Jang DP, Kim IY, Cho SH. Altered Quality of Life and Psychological Health (SCL-90-R) in Patients With Chronic Rhinosinusitis With Nasal Polyps. Ann Otol Rhinol Laryngol. 2015 Mar 5. pii: 0003489415576181. [Epub ahead of print]  PMID: 25743178
• K. Kollndorfer, A. Jakaba, C.A. Muellerc, S. Trattnigd, V. Schöpfa, e, f, - Effects of chronic peripheral olfactory loss on functional brain networks Neuroscience, 28 September 2015
• Patterson A, Hähner A, Kitzler HH, Hummel T. Are small olfactory bulbs a risk for olfactory loss following an upper respiratory tract infection? Eur Arch Otorhinolaryngol (2015) 272: 3593
• Philpott CM, Boak D. - The impact of olfactory disorders in the United Kingdom. Chem Senses. 2014 Oct;39(8):711-8. doi:10.1093/chemse/bju043. Epub 2014 Sep 8. PMID: 25201900.
• Kollndorfer K, Kowalczyk K, Hoche E, Mueller CA, Pollak M, Trattnig S, Schöpf V. Recovery of olfactory function induces neuroplasticity effects in patients with smell loss. Neural Plasticity,Volume 2014, Article ID 140419
• Croy I, Nordin S, Hummel T. Olfactory disorders and quality of life--an updated review. Chemical Senses, Volume 39, Issue 3, 1 March 2014
• Croy I, Hoffmann H, Philpott C, Rombaux P, Welge-Luessen A, Vodicka J, Konstantinidis I, Morera E, Hummel T. -  Retronasal testing of olfactory function: an investigation and comparison in seven countries. Meat Sci. 2013 Aug;94(4):425-31. doi: 10.1016/j.meatsci.2013.03.020. Epub 2013 Mar 28. PMID: 23611883
• Sánchez-Vallecillo MV, Fraire ME, Baena-Cagnani C, Zernotti ME. - Olfactory dysfunction in patients with chronic rhinosinusitis. Int J Otolaryngol. 2012;2012:327206. doi: 10.1155/2012/327206. Epub 2012 May 20. PMID: 22685462
• Bonfils P, Avan P, Faulcon P, Malinvaud D. - Distorted odorant perception: analysis of a series of 56 patients with parosmia. Arch Otolaryngol Head Neck Surg. 2005;131(2):107-112. doi:10.1001/archotol.131.2.107